Proteomic analysis of azole resistance in Candida albicans clinical isolates.
نویسندگان
چکیده
Changes in protein expression within a matched set of Candida albicans isolates representing the acquisition of azole resistance were examined by two-dimensional polyacrylamide gel electrophoresis and peptide mass fingerprinting. Proteins differentially expressed in association with azole resistance included Grp2p, Ifd1p, Ifd4p, Ifd5p, and Erg10p, a protein involved in the ergosterol biosynthesis pathway.
منابع مشابه
MUTATION IN HOTSPOT REGIONS OF THE ERG11 GENE AND FLUCONAZOLE RESISTANCE IN CLINICAL ISOLATES OF CANDIDA ALBICANS IN RASHT CITY
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 7 شماره
صفحات -
تاریخ انتشار 2004